BACKGROUND: Genetic analysis in the mouse revealed that GREMLIN1 (GREM1)-mediated antagonism of BMP4 is essential for ureteric epithelial branching as the disruption of ureteric bud outgrowth and renal agenesis in Grem1-deficient embryos is restored by additional inactivation of one Bmp4 allele. Another BMP ligand. BMP7. was shown to control the proliferative expansion of nephrogenic ... https://www.roneverhart.com/Western-Digital-Ultrastar-DC-HC570-WUH722222ALE6L1-22TB-7-2K-RPM-SATA-6Gb-s-512e-SED-3-5in-Recertified-Hard-Drive/